| 2009-10 New England Patriots Schedule |
| Date | Opponent | Time | TV | W/L | Score |
|---|---|---|---|---|---|
| 9/14/09 | Bills | 7:00 PM | WCVB | 25-24 | |
| 9/20/09 | @ Jets | 4:15 PM | CBS | 9-16 | |
| 9/21/09 | Falcons | 1:00 PM | FOX | 26-10 | |
| 10/04/09 | Ravens | 1:00 PM | CBS | 27-21 | |
| 10/11/09 | @ Broncos | 4:15 PM | CBS | 17-20 | |
| 10/18/09 | Titans | 4:15 PM | CBS | 59-0 | |
| 10/25/09 | @ Buccaneers | 1:00 PM | CBS | 35-7 | |
| 11/01/09 | Bye | ||||
| 11/08/09 | Dolphins | 1:00 PM | CBS | 27-17 | |
| 11/15/09 | @ Colts | 8:20 PM | NBC | 34-35 | |
| 11/22/09 | Jets | 4:15 PM | CBS | 31-14 | |
| 11/30/09 | @ Saints | 8:30 PM | WCVB | 17-38 | |
| 12/06/09 | @ Dolphins | 8:20 PM | NBC | 21-22 | |
| 12/13/09 | Panthers | 1:00 PM | FOX | 20-10 | |
| 12/20/09 | @ Bills | 1:00 PM | CBS | 17-10 | |
| 12/27/09 | Jaguars | 1:00 PM | CBS | 35-7 | |
| 1/3/10 | @ Texans | 1:00 PM | CBS | 27-34 | |
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